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CASE SERIES
Year : 2022  |  Volume : 11  |  Issue : 2  |  Page : 105-109

A case series study of omphalocele with associated anomalies: An embryogenic imperfection


1 Associate Professor, Department of Pathology, Bhaskar Medical College and General Hospital, KNR University of Health Science, Hyderabad, Telangana, India
2 Assistant Professor, Department of Anatomy, Mamata Academy of Medical Science, KNR University of Health Sciences, Bachupally, Hyderabad, Telangana, India
3 HOD and Professor, Department of Anatomy, Kamineni Academy of Medical Sciences and Research Centre, KNR University of Health Science, Hyderabad, Telangana, India
4 Lecturer, Department of Anatomy, Kamineni Academy of Medical Sciences and Research Centre, KNR University of Health Science, Hyderabad, Telangana, India

Correspondence Address:
Kasturi Kshitija
Bhaskar Medical College and General Hospital, Hyderabad-500075, Telangana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/NJCA.NJCA_29_22

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Omphalocele is a developmental aberration which occurs during embryonic period in the fetal life. The fault in complete closure of the anterior abdominal wall leading to protrusion of the abdominal viscera mainly the small and large intestines with the liver into the base of umbilical cord insertion forms its main pathological feature. It differs from gastroschisis in that the eviscerated organs are covered by a thin amniotic peritoneal membrane, whereas in latter, the herniated contents are exposed exterior with no covering. In fetuses, this malformation is known to be complicated with abnormal karyotyping, other congenital abnormalities, and idiopathic syndromes which account for grave prognosis. Hence, the aim of our study was to analyze the clinical presentation and document seven cases of fetuses having omphalocele associated with anomalies and chromosomal aberrations leading to fetal dismissal.


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